Optimized Molecular Results
LeanDECAL is a cutting-edge instrument that automates fixation and decalcification to deliver superior bone marrow results. By combining precise temperature control with advanced automation, LeanDECAL standardizes and accelerates these processes, streamlining laboratory workflows and ensuring consistent, high-quality outcomes that surpass traditional manual methods. Optimized for use with Milestone’s MoL-Decalcifier, an unbuffered EDTA, LeanDECAL enhances decalcification efficiency, preserves RNA and DNA integrity, and supports exceptional molecular analysis results.
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FIXATIVE TANK
for the fixation phase
RINSING TANK
DECALCIFIER TANK
SECOND RINSING / HOLDING TANK
TOUCHSCREEN TERMINAL
2 USB PORTS
CASSETTE CAVITY
WORKING AREA
DEDICATED RACK
with 20 cassette capacity
Workflow Optimization
LeanDECAL provides a fully automated, standardized solution for fixation and decalcification. It features a temperature-controlled processing chamber with an integrated magnetic stirrer, ensuring even reagent distribution and consistent flow across the bone marrow surface. Operating autonomously, the system dispenses reagents into the chamber and returns them to designated tanks after each step. Operators simply select the appropriate protocol for the specimen, ensuring reliable, high-quality results with every cycle.
Enhanced Specimen Safety
LeanDECAL ensures unparalleled specimen safety through an advanced suite of integrated features designed for reliability and precision:
- Temperature Sensor: Continuously monitors reagent temperature to maintain optimal conditions.
- Reagent Level Sensors: Precisely track reagent volume within the cavity for consistent performance.
- Cover Sensor: Ensures secure cavity closure during operation for maximum safety.
- Specimen Cavity Filter: Effectively captures potential debris to protect sample integrity.
- Spillage Tray: Positioned beneath the system, it safely collects any reagent spills to prevent hazards.
In addition, LeanDECAL provides real-time updates on reagent lifespan and usage, issuing timely alerts for replacements. Operators are guided through a streamlined procedure, including scanning tank barcodes, to ensure complete traceability and compliance.
Full Documentation
LeanDECAL provides robust documentation for every process, enabling seamless data transfer to a USB drive or printing for quality assurance and regulatory compliance. Key documented elements include:
- Saved Runs: Detailed records of all completed processes include:
- Fixatives/Decalcification Solutions Used
- Time and Date of Fixation/Decalcification Run
- Duration and Temperature of Fixation/Decalcification Phase
- Events log: A comprehensive record of system activities and operational events.
- Reagents log: Detailed tracking of reagent usage and status for inventory management.
The Ideal Partner for Superior Decalcification
Milestone’s MoL-DECALCIFIER, an EDTA-based solution, is expertly formulated with a balanced blend of dibasic and tribasic EDTA, maintaining an optimal pH range of 7.2–7.4 for rapid decalcification without the need for acid buffers. When paired with LeanDECAL’s closed-system technology, MoL-DECALCIFIER maximizes molecular yield, ensuring high-quality decalcification. This powerful combination enables your lab to achieve exceptional results while maintaining efficient turnaround times to support timely patient care.
Optimal Quality
Standardized protocols and specialized reagents ensure optimal results while preserving tissue morphology and immunohistochemical analysis. In molecular studies, a cornerstone of diagnostic workflows, EDTA enhances the quantity and quality of nucleic acids, safeguarding critical material for biomarker-targeted therapies and gene expression profiling.
*(Singh et al., 2013, “Analysis of the effect of various decalcification agents on the quantity and quality of nucleic acid [DNA and RNA] recovered from bone biopsies”)
